Global disease prevalence: Vaginal cancer is a rare malignancy of the female reproductive system worldwide; it is relatively more common in elderly women and accounts for a small proportion of gynecological tumors.

Treatment of vaginal cancer by stage
Early treatment (involving a localized, smaller tumor with a favorable response)
consisting of surgical resection combined with adjuvant therapy—can effectively control tumor progression while preserving vaginal function.
Treatment for the intermediate stage (involving local spread; aiming to inhibit growth and delay progression)
employs a comprehensive approach—such as surgery combined with radiotherapy and chemotherapy—to control further tumor spread while preserving vaginal function to the greatest extent possible.
Treatment for advanced-stage disease (involving distant metastasis, symptom relief, and survival prolongation)
primarily relies on systemic therapies such as radiotherapy and chemotherapy to alleviate clinical symptoms and extend patient survival as much as possible.
Consequences of failing to receive timely treatment in the early stage: If standardized treatment is not administered promptly in the early stage, the tumor will continue to grow and spread/metastasize to surrounding tissues and distant organs, resulting in a missed opportunity for optimal intervention.
Why choose Fosun Health for vaginal cancer treatment
Fosun Health’s vaginal cancer diagnosis and treatment services are managed by a specialized gynecologic oncology center; the team possesses extensive experience in vaginal-sparing surgery, brachytherapy, and comprehensive treatment for advanced-stage disease.Leveraging a global medical network, patients can access state-of-the-art international treatments such as radical surgery for vaginal cancer, minimally invasive laparoscopic surgery, intensity-modulated radiotherapy (IMRT), intracavitary brachytherapy, targeted therapy, and immunotherapy.
For complex cases such as advanced or recurrent vaginal cancer, a multidisciplinary team (MDT)—comprising experts in gynecologic oncology, radiation oncology, medical oncology, and radiology—collaborates to formulate the optimal treatment plan; a cross-border consultation mechanism enables patients to obtain second opinions from leading international centers.
Foshan Fosun Chancheng Hospital is equipped with the CyberKnife M6 precision radiotherapy system and the VitalBeam linear accelerator, enabling the delivery of stereotactic radiosurgery and intracavitary brachytherapy.The hospital's gynecologic oncology team possesses extensive experience in function-sparing treatment for vaginal cancer, offering patients personalized, comprehensive care that integrates surgery, radiotherapy, and systemic therapy.

Vaginal Cancer Treatment Methods
1.Surgical treatment for vaginal cancer
For certain cases of early-stage, localized vaginal cancer or recurrent lesions, local excision, vaginectomy, or other appropriate surgical procedures may be selected based on tumor location, extent, and the patient's overall condition.
Treatment advantages:
① Direct resection: For localized lesions, the tumor can be directly resected.
② Obtain pathology: Surgical tissue can be used for pathological staging and margin assessment.
③ Local control: Enables local tumor ablation for lesions that meet surgical indications.
④ Personalized surgery: Select a surgical approach based on tumor location, extent of invasion, and history of prior treatment.
2.CyberKnife precision radiotherapy
For selected lesions involving localized recurrence, oligometastasis, or other conditions indicating stereotactic radiotherapy, CyberKnife treatment may be considered following multidisciplinary evaluation; however, it is not the standard first-line treatment for all patients with vaginal cancer.
Treatment advantages:
① Precise localization: Formulate a local radiotherapy plan based on the location of the lesion.
② Non-surgical treatment: No traditional surgical incision required.
③ Dose concentration: Concentrates the radiation dose on the target lesion.
④ Applicable to specific lesions: Can provide a treatment option for specific localized lesions or local recurrences following prior treatment.
3. VitalBeam linear accelerator precision radiotherapy
Utilizing the VitalBeam linear accelerator platform, precise external beam radiotherapy can be administered based on the extent of primary vaginal lesions and pelvic lymph nodes.
Treatment advantages:
① Precision irradiation: Formulate a radiotherapy plan based on the extent of the tumor and lymphatic drainage regions.
② Dose optimization: Optimizes target area coverage and dose distribution.
③ Protects normal tissues: Minimizes radiation exposure to organs such as the bladder, rectum, and small intestine as much as possible.
④ Suitable for comprehensive radiotherapy: Can be combined with modalities such as brachytherapy and chemotherapy.
4.Brachytherapy
Involves local irradiation by placing a radiation source near the vaginal tumor; treatment plans are tailored based on tumor location and external beam radiotherapy protocols.
Treatment advantages:
① Concentration of local dose: Concentrating a higher radiation dose on the tumor and its adjacent regions.
② Precision therapy: Personalized treatment is administered based on tumor location and size.
③ Reduce distant radiation exposure: Helps lower radiation exposure to normal tissues located away from the treatment area.
④ Combination therapy: Can be combined with external beam radiotherapy for select vaginal cancer patients.
5.Chemotherapy
Systemic elimination of potential cancer cells using anti-cancer drugs; often combined with radiotherapy to enhance efficacy and control distant metastasis; achieves effective therapeutic results.
6.Immunotherapy
Activates the body's immune system to recognize and attack cancer cells, providing a new, effective treatment option for patients with advanced vaginal cancer to improve therapeutic efficacy.
7.Targeted therapy
Delivers precision strikes against specific molecular targets; offers good efficacy with relatively mild side effects; suitable for select patients with advanced-stage disease.Helps improve therapeutic outcomes.
8.Comprehensive therapy
Formulate an individualized comprehensive treatment plan based on the patient's specific condition, combining modalities such as radiotherapy, surgery, and chemotherapy to enhance therapeutic efficacy.
9.Supportive care
Approaches such as nutritional support, psychological counseling, and symptom management can comprehensively improve the patient's physical condition and quality of life, as well as consolidate therapeutic efficacy.
Post-treatment care
Maintain vulvar hygiene and a regular daily routine; avoid resuming sexual activity too soon; attend scheduled follow-up appointments and actively cooperate with subsequent treatment as advised.
Post-treatment examinations
Periodic gynecological examinations, tumor marker testing, and follow-up imaging are required after treatment to timely detect changes in the disease status.
Conclusion
Vaginal cancer poses a serious threat; the key to treatment lies in early detection, diagnosis, and intervention. Selecting an appropriate treatment plan and adhering to follow-up care helps improve quality of life.

