Global disease prevalence: Glioma is a common primary brain tumor worldwide; it has a high incidence rate among adults, and high-grade gliomas carry a poor prognosis.
Staging-based treatment for gliomas
Early treatment (involving a localized, small tumor with a favorable response)
specifically surgical resection combined with adjuvant therapy—can effectively control tumor progression, and the patient's prognosis is relatively good.
Treatment for the intermediate stage (involving local spread; aiming to inhibit growth and delay progression)
employs a comprehensive approach—such as surgery combined with radiotherapy and chemotherapy—to control further tumor spread and slow the rate of disease deterioration.
Treatment for advanced disease (distant metastasis; aimed at symptom relief and survival prolongation)
primarily employs systemic therapies such as chemoradiotherapy, targeted therapy, and others to alleviate clinical symptoms and extend patient survival as much as possible.
Why choose Fosun Health for glioma treatment
Leveraging the neurosurgery, M6 CyberKnife, VitalBeam, Tumor Treating Fields (TTFields), and molecular pathology platforms of its affiliated hospitals, Fosun Health facilitates multidisciplinary consultations involving experts in neurosurgery, radiotherapy, medical imaging, pathology, medical oncology, and rehabilitation.Based on tumor location, WHO grading, extent of resection, and biomarkers such as IDH, 1p/19q, and MGMT, the team formulates a treatment plan involving surgery, radiotherapy, chemotherapy, or Tumor Treating Fields therapy.
Precision surgery and radiotherapy emphasize protecting critical areas—such as speech and motor centers, visual pathways, and the brainstem—while minimizing radiation exposure to normal brain tissue to reduce the risk of adverse effects on neurological and cognitive functions.Fosun Health provides continuous, one-stop medical support covering everything from diagnosis and treatment to the management of epilepsy and cerebral edema, as well as speech, motor, and cognitive rehabilitation.
Glioma treatment methods
1.M6 CyberKnife treatment
Uses robotic multi-angle focused radiation to target localized enhancing nodules; suitable for small-volume residual disease, nodular recurrence, or selective re-irradiation of lesions following MDT assessment.
Treatment advantages:
① Targeting localized target areas: Suitable for select recurrent nodules with relatively clear boundaries.
② Protect normal brain tissue: Reduce radiation dose to the brainstem, visual pathways, and functional areas.
③ Hypofractionated treatment: Reduces the impact of re-treatment on recovery and pharmacological therapy.
④ Does not replace standard radiotherapy: Diffuse gliomas still require evaluation for larger-field irradiation.
2.VitalBeam precision radiotherapy
Uses image-guided intensity-modulated radiotherapy (IMRT) to target the surgical cavity, residual tumor, and high-risk infiltration zones identified on MRI; suitable for postoperative adjuvant therapy, unresectable cases, or patients with partial recurrence.
Treatment advantages:
① Covers areas of infiltration: Addresses surgical cavities, residual tumors, and high-risk brain tissue.
② Protection of functional areas: Reduces radiation dose to the brainstem, visual pathways, hippocampus, and normal brain tissue.
③ Facilitates concurrent therapy: Can be integrated with drug therapies such as temozolomide.
④ Supports re-treatment assessment: Treatment plans are formulated based on prior radiation doses and the extent of recurrence.
3.Tumor Treating Fields (TTFields) therapy
Uses scalp electrodes to apply an alternating electric field at a specific frequency, disrupting tumor cell division; primarily indicated for newly diagnosed or recurrent supratentorial glioblastoma.
4.Microsurgical maximal safe resection
Resect the tumor as extensively as possible while preserving vital functions such as speech and movement, and obtain tissue samples for pathological and molecular diagnosis.
5.Chemotherapy
Uses anticancer drugs such as temozolomide to kill cancer cells and effectively control the rate of tumor progression; commonly used for patients with high-grade glioma.
6.Targeted therapy
Precision targeting of specific molecular markers offers favorable efficacy and relatively mild side effects, making it suitable for select patients with recurrent glioma.
Post-treatment care
Maintain a regular daily routine and a balanced diet; avoid strenuous exercise; attend scheduled follow-up appointments and actively cooperate with subsequent treatment as advised.
Post-treatment examinations
Periodic cranial MRI, tumor marker testing, and neurological function assessments are required after treatment to timely detect changes in the disease status.
Conclusion
Cerebral glioma poses a serious threat; successful treatment hinges on early detection, diagnosis, and intervention, as well as selecting an appropriate treatment plan and adhering to follow-up care to improve quality of life.
