Prevalence worldwide
Buccal mucosal cancer is a common oral malignancy worldwide, with higher incidence in some parts of Asia and a close association with unhealthy habits.

Buccal mucosal cancer treatment by stage
Early-stage treatment (localized tumor, tumor shrinkage, good response)
Surgical removal combined with adjuvant treatment effectively controls tumor progression and preserves normal oral function.
Intermediate-stage treatment (local spread, growth inhibition, delayed progression)
Surgery combined with chemoradiotherapy and other modalities controls further tumor spread while preserving oral function as much as possible.
Treatment for advanced-stage disease (involving distant metastasis, symptom relief, and survival prolongation)
primarily relies on systemic therapies such as radiotherapy and chemotherapy to alleviate clinical symptoms and extend patient survival as much as possible.
Consequences of failing to receive timely treatment in the early stage: If standardized treatment is not administered promptly in the early stage, the tumor will continue to grow and spread/metastasize to surrounding tissues and distant organs, resulting in a missed opportunity for optimal intervention and a worsening of the condition.
Why choose Fosun Health for buccal mucosal cancer treatment
Fosun Health draws on its hospitals' head and neck surgery, oral and maxillofacial reconstruction, M6 CyberKnife, VitalBeam, and pathology platforms to organize multidisciplinary consultations involving head and neck surgery, radiotherapy, imaging, pathology, dentistry, and medical oncology specialists. The team coordinates surgery, radiotherapy, or systemic treatment based on tumor stage, margins, invasion depth, and nerve, vascular, and lymph node status.
Precision radiotherapy covers the surgical bed, perineural pathways, and high-risk neck regions while minimizing exposure of the mandible, salivary glands, oral mucosa, and swallowing structures, reducing some risks of dry mouth, restricted mouth opening, and mandibular injury. Fosun Health provides continuous medical support from pretreatment dental assessment to oral care, mouth-opening training, swallowing rehabilitation, and nutritional recovery.

Buccal mucosal cancer treatment methods
1.M6 CyberKnife treatment
Real-time imaging verification and robotic irradiation from multiple angles are suitable for patients with small local recurrences, residual lesions, or oligometastases when conventional reirradiation cannot adequately protect surrounding tissue.
Treatment advantages:
①Focuses on localized lesions: Suitable for small recurrent lesions with relatively clear boundaries.
②Protects oral structures: Reduces doses to the mandible, salivary glands, and oral mucosa.
③Reduces functional impact: Lessens interference with mouth-opening, chewing, and eating training.
④Careful risk assessment: Focuses on preventing mucosal ulcers, osteonecrosis, and bleeding.
2.VitalBeam precision radiotherapy
Image-guided and intensity-modulated radiotherapy treats the buccal mucosal surgical bed, adjacent invaded tissues, and cervical lymph nodes, suitable for high-risk postoperative, unresectable, or recurrent disease.
Treatment advantages:
①Adapts to irregular targets: Covers the surgical bed, perineural pathways, and high-risk neck regions.
②Protects the mandible: Reduces radiation-related bone injury risk.
③Preserves salivary and swallowing function: Reduces doses to the parotid glands, oral cavity, and pharyngeal constrictors.
④Facilitates combined treatment: Can be coordinated with surgery, concurrent chemotherapy, or immunotherapy.
3.Buccal mucosal cancer resection, neck dissection, and oral and maxillofacial reconstruction
Suitable for resectable early or locally advanced buccal mucosal cancer. Tumor removal, necessary neck treatment, and tissue reconstruction are performed according to invasion extent.
4.Chemotherapy
Minimally invasive techniques precisely remove tumor lesions with less trauma while better preserving oral chewing and speech functions.
5.Immunotherapy
Formulate an individualized comprehensive treatment plan—combining surgery, chemoradiotherapy, and other modalities based on the patient's specific condition—to enhance therapeutic efficacy.
6Seed implantation:
Suitable for patients with residual or recurrent buccal mucosal cancer, limited options for surgery and external beam radiotherapy, and clearly defined lesion extent after multidisciplinary evaluation.
Follow-up care after treatment
Maintain oral cleanliness and food hygiene, avoid spicy and irritating foods, attend regular follow-up appointments as instructed, and actively cooperate with subsequent treatment.
Post-treatment examinations
Regular oral examinations, tumor marker testing, and follow-up imaging are needed to detect abnormal changes promptly.
Conclusion
Buccal mucosal cancer is a serious disease. Early detection, diagnosis, and intervention are central to treatment. An appropriate treatment plan and continued follow-up help improve quality of life and prolong survival.

